The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five ...

Following new injury reports, updated simulations reveal the best bet for 49ers vs. Bills on Sunday Night Football. Injury ...

The San Francisco 49ers reportedly made a move on Friday. According to Eric Branch of The San Francisco Chronicle, the 49ers ...

Preview the Week 13 matchup between the Buffalo Bills and San Francisco 49ers with predictions, odds, over/under, spread, ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

Taking the field in Week 1 with sky-high expectations, what with eight-year head coach Kyle Shanahan having just taken his ...

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

San Francisco 49ers quarterback Brock Purdy is poised to return to action on Sunday night against the Buffalo Bills after ...

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

If the 49ers can't break out of their funk, here are three maneuvers they should consider down the home stretch.