The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

Purdy missed the 49ers' Week 12 contest versus the Green Bay Packers last Sunday with a right shoulder injury—a game San ...

San Francisco 49ers quarterback Brock Purdy is expected to return to the field on Sunday against the Buffalo Bills after ...

A light dusting of snow began covering the Buffalo Bills' facility on Friday as the team completed its final practice of the ...

Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

Preview the Week 13 matchup between the Buffalo Bills and San Francisco 49ers with predictions, odds, over/under, spread, ...

San Francisco 49ers quarterback Brock Purdy will return to the starting lineup Sunday against the Buffalo Bills, Kyle ...

A good ol' fashioned lake effect snowstorm is burying western New York this weekend when the Buffalo Bills and San Francisco ...

Buffalo Bills coach Sean McDermott ruled out Dalton Kincaid from playing against San Francisco on Sunday night, while holding ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...